From the Game's Introduction:
What is Fatale? Fatale is a storytelling game about a cunning, sensual woman and her unwitting, hopeful amours. It's rather like an improvised play if you need an analogy; a passion play perhaps? Each player takes the part of one character in the ensuing drama, speaking their lines and describing what they are doing.
It's also a deadly game of cat-and-mouse. Your lady firend may be fantastically beautiful and seductive, but you are dancing with a viper, and she could strike at any moment. When any dangerous action is attempted, it is the dice that will decide if the player's alter ego comes through the experience unscathed.